The Criteria For Selecting Medication For any Patient

SINCE World War II, medical science has progressed to a stage where competitive medications are for sale to treat exactly the same ailment in several people. It’s not just about brands (the trade issue) but generic drugs (the scientific issue). Within this report, we shall glance at the various factors that decide the selection of a particular drug.

Safety: These sub-criteria must be considered within the criterion of safety:

* Acute therapeutic index: If the patient’s condition is acute, how effective is often a particular drug regardless of whether it’s got certain side-effects so long as the acuteness with the condition is lowered? Example: narcotic pain-killers are very effective in healing pain but include the potential side-effect of addiction.

* Long-term safety: drug directory might be safe in short-term treatment, but how safe it is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but could have undesirable effects in case there is prolonged use.

* Drug-drug interaction risk: Prescription medication is chemicals, and many chemicals answer make a different chemical, which has an effect that could harm the sufferer or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to generate a new condition that warrants separate treatment.

Drug-drug interaction risk is of two kinds:

· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, separate from the other, have certain effects using one or more body processes (e.g., metabolism) that affects the performance with the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the action of a liver enzyme that Lexapro (escitalopram) is determined by for the metabolism. This causes a boost in the side-effects of Lexapro.

· Pharmacodynamic: Here, 2 or more drugs actually create the same relation to exactly the same organ, thus increasing the total, added effect. Example: Lexapro has certain side-effects for example drowsiness and fatigue. Darvocet-N also acts similarly for the brain. Thus, the side-effects of the two drugs are more serious.

Tolerability: A drug might be effective however, not tolerable by all patients. Example: Allergies to specific drugs in certain people. Short-term and long-term tolerability need to be considered. Efficacy: A drug isn’t equally great at all patients. By way of example, some patients with depression or panic disorders experience rest from escitalopram, but there are several who don’t, who therefore need to be prescribed another anti-depressant. The pace of oncoming of therapeutic action is a vital step to be regarded too.

Cost: Cost doesn’t imply the price tag on acquiring a specific medicine alone. It must also cover the price tag on management of a complication that could arise while using another drug. Example: Within a individual that insists on taking alcohol nevertheless must be treated for depression is normally administered an SSRI drug since these drugs don’t potentiate the effects of alcohol, whereas another group of anti-depressants (for example tricyclics) could cause a new problem in such patients, which could need a different and expensive treatment. Therefore, it’s preferable to prescribe the more costly escitalopram as opposed to a cheaper tricyclic in such patients.

Simplicity of treatment: Most effective mode of administration is preferred. If you find an option between an injection and oral administration, rogues is preferred if the efficacy of the two modes is analogous. Or, local application is chosen over the oral route where possible; e.g., antibiotic management of eye infections. Dosage and frequency of administration too are an important factor to choose simplicity of treatment.
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