The factors For selecting Medication For the Patient
SINCE The second world war, medical science has progressed into a stage where competitive medications are around to treat the identical ailment in different people. This is simply not just about brands (the trade issue) but generic drugs (the scientific issue). With this report, we shall go through the various factors that decide selecting a particular drug.
Safety: The next sub-criteria have to be considered beneath the criterion of safety:
* Acute therapeutic index: If your patient’s condition is acute, how effective is really a particular drug even though they have certain side-effects as long as the acuteness with the condition is lowered? Example: narcotic pain-killers work well in healing pain but come with the potential side-effect of addiction.
* Long-term safety: http://medicationdirectory.com could be safe in short-term treatment, but exactly how safe it can be in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but can have undesirable effects in the event of prolonged use.
* Drug-drug interaction risk: Medicine is chemicals, and a lot of chemicals answer produce a different chemical, which has an effect that could harm the sufferer or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to produce a new condition that warrants separate treatment.
Drug-drug interaction risk is of two sorts:
· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, separate from the other person, have certain effects on a single or maybe more body processes (e.g., metabolism) that affects the performance with the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the action of a liver enzyme that Lexapro (escitalopram) is dependent upon due to the metabolism. This will cause more the side-effects of Lexapro.
· Pharmacodynamic: Here, two or more drugs actually make the same effect on the identical organ, thus helping the total, added effect. Example: Lexapro has certain side-effects including drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of the two prescription medication is more intense.
Tolerability: A drug could be effective although not tolerable by all patients. Example: Allergies to a particular drugs in most people. Short-term and long-term tolerability must be taken into consideration. Efficacy: A drug just isn’t equally great at all patients. As an example, some patients with depression or panic attacks experience respite from escitalopram, but there are numerous that don’t, who therefore must be prescribed another anti-depressant. The speed of oncoming of therapeutic action is an important the answer to be regarded too.
Cost: Cost does not always mean the price tag on acquiring some medicine alone. It should also cover the price tag on treatment of a complication that could arise from utilizing another drug. Example: In a individual who insists on taking alcohol but must be treated for depression is normally administered an SSRI drug since these drugs don’t potentiate the consequences of alcohol, whereas another number of anti-depressants (including tricyclics) might cause a new problem in such patients, which may require a various and expensive treatment. Therefore, it’s preferable to prescribe the more costly escitalopram instead of a cheaper tricyclic in such patients.
Simple treatment: The simplest mode of administration is preferred. When there is an alternative between a shot and oral administration, the latter is preferred when the efficacy of the two modes is analogous. Or, local application is chosen over the oral route where possible; e.g., antibiotic treatment of eye infections. Dosage and frequency of administration too are an important factor to determine simplicity of treatment.
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