The requirements For Selecting Medication For A Patient

SINCE World war 2, medical science has progressed to a stage where competitive medications are available to treat exactly the same ailment in numerous people. This isn’t almost brands (the industry trade issue) but generic drugs (the industry scientific issue). In this report, we shall look at the various factors that decide picking a a particular drug.

Safety: The subsequent sub-criteria has to be considered within the criterion of safety:

* Acute therapeutic index: If the patient’s condition is acute, how effective is a particular drug even though they have certain side-effects so long as the acuteness of the condition is lowered? Example: narcotic pain-killers are incredible in healing pain but feature the potential side-effect of addiction.

* Long-term safety: medicine directory might be safe in short-term treatment, but wait, how safe it is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but could have undesirable effects in case of prolonged use.

* Drug-drug interaction risk: Prescription medication is chemicals, and several chemicals respond to develop a different chemical, that have an effect that could harm the patient or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to generate a new condition that warrants separate treatment.

Drug-drug interaction risk is of two kinds:

· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, independent of the other, have certain effects using one or even more body processes (e.g., metabolism) that affects the performance of the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the action of a liver enzyme that Lexapro (escitalopram) is dependent upon for the metabolism. This leads to an increase in the side-effects of Lexapro.

· Pharmacodynamic: Here, two or more drugs actually create the same relation to exactly the same organ, thus enhancing the total, added effect. Example: Lexapro has certain side-effects including drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of both drugs are more intense.

Tolerability: A medication might be effective but not tolerable by all patients. Example: Allergies to specific drugs in most people. Short-term and long-term tolerability must be taken into consideration. Efficacy: A medication just isn’t equally great at all patients. For instance, some patients with depression or panic attacks experience relief from escitalopram, but there are numerous that don’t, who therefore must be prescribed a different anti-depressant. The rate of start of therapeutic action is an important the answer to be considered too.

Cost: Cost doesn’t imply the price tag on acquisition of some medicine alone. It must also cover the price tag on treatments for a complication that could arise by using a different drug. Example: In a one who insists on taking alcohol but should be treated for depression is generally administered an SSRI drug because they drugs don’t potentiate the effects of alcohol, whereas another gang of anti-depressants (including tricyclics) can cause a fresh overuse injury in such patients, which may need a different and expensive treatment. Therefore, it’s preferable to prescribe the more costly escitalopram rather than a cheaper tricyclic in this patients.

Simple treatment: The best mode of administration is preferred. When there is an alternative between a shot and oral administration, aforementioned is preferred in the event the efficacy of both modes is analogous. Or, local application is preferred to the oral route where possible; e.g., antibiotic treatments for eye infections. Dosage and frequency of administration too are a key point to choose simplicity of treatment.
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