The requirements For selecting Medication For any Patient

SINCE World war 2, medical science has progressed into a stage where competitive medications are for sale to treat the identical ailment in different people. This is simply not nearly brands (which is a trade issue) but generic drugs (which is a scientific issue). Within this report, we shall consider the various factors that decide picking a a certain drug.

Safety: These sub-criteria must be considered beneath the criterion of safety:

* Acute therapeutic index: If the patient’s condition is acute, how effective can be a particular drug regardless of whether it’s got certain side-effects so long as the acuteness from the condition is lowered? Example: narcotic pain-killers are very effective in healing pain but feature the possible side-effect of addiction.

* Long-term safety: drug could be safe in short-term treatment, but how safe it’s in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but can have undesirable effects in the case of prolonged use.

* Drug-drug interaction risk: Prescription medication is chemicals, and lots of chemicals respond to make a different chemical, which has an effect that may harm the individual or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to produce a new condition that warrants separate treatment.

Drug-drug interaction risk is of 2 types:

· Pharmacokinetic: In this type of drug-drug interaction, two drugs, independent of each other, have certain effects using one or more body processes (e.g., metabolism) that affects the performance from the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) depends upon for its metabolism. This leads to a boost in the side-effects of Lexapro.

· Pharmacodynamic: Here, 2 or more drugs actually create the same relation to the identical organ, thus helping the total, added effect. Example: Lexapro has certain side-effects for example drowsiness and fatigue. Darvocet-N also acts similarly for the brain. Thus, the side-effects of both medicines are more serious.

Tolerability: A medicine could be effective however, not tolerable by all patients. Example: Allergies to certain drugs in some people. Short-term and long-term tolerability have to be considered. Efficacy: A medicine is not equally great at all patients. For example, some patients with depression or panic attacks experience respite from escitalopram, but there are several who don’t, who therefore have to be prescribed some other anti-depressant. The rate of start of therapeutic action is a vital the answer to be looked at too.

Cost: Cost does not always mean the expense of acquisition of a particular medicine alone. It ought to also cover the expense of treatments for a complication that may arise from using some other drug. Example: Within a one who insists on taking alcohol yet needs to be treated for depression is often administered an SSRI drug as these drugs don’t potentiate the results of alcohol, whereas another band of anti-depressants (for example tricyclics) can cause a whole new problem in such patients, which would have to have a various and expensive treatment. Therefore, it’s better to prescribe the more costly escitalopram instead of a cheaper tricyclic in these patients.

Simplicity of treatment: The best mode of administration is preferred. If you have a choice between a shot and oral administration, the second is preferred if your efficacy of both modes is the identical. Or, local application is preferred to the oral route where possible; e.g., antibiotic treatments for eye infections. Dosage and frequency of administration too are an important factor to decide simple treatment.
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