The requirements For Selecting Medication For any Patient
SINCE World war 2, medical science has progressed to a stage where competitive medications are for sale to treat the identical ailment in several people. This is simply not almost brands (the trade issue) but generic drugs (the scientific issue). In this report, we shall look at the various factors that decide your selection of a selected drug.
Safety: The subsequent sub-criteria has to be considered underneath the criterion of safety:
* Acute therapeutic index: In the event the patient’s condition is acute, how effective is a particular drug even if they have certain side-effects as long as the acuteness in the condition is lowered? Example: narcotic pain-killers are incredible in healing pain but feature the possible side-effect of addiction.
* Long-term safety: http://medicationdirectory.com may be safe in short-term treatment, but wait, how safe it’s in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but could have undesirable effects in the case of prolonged use.
* Drug-drug interaction risk: Medicines are chemicals, and lots of chemicals respond to make a different chemical, which has an effect which could harm the person or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to make a new condition that warrants separate treatment.
Drug-drug interaction risk is of two types:
· Pharmacokinetic: In this type of drug-drug interaction, two drugs, outside of the other, have certain effects using one or even more body processes (e.g., metabolism) that affects the performance in the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) depends on for its metabolism. This leads to a boost in the side-effects of Lexapro.
· Pharmacodynamic: Here, 2 or more drugs actually generate the same effect on the identical organ, thus increasing the total, added effect. Example: Lexapro has certain side-effects like drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of the medicines are more intense.
Tolerability: A drug may be effective however, not tolerable by all patients. Example: Allergies to particular drugs in a few people. Short-term and long-term tolerability should be looked at. Efficacy: A drug is just not equally great at all patients. For instance, some patients with depression or anxiety disorders experience reduced escitalopram, but there are many who don’t, who therefore should be prescribed an alternative anti-depressant. The pace of oncoming of therapeutic action is an important factor to be looked at too.
Cost: Cost does not always mean the price tag on acquisition of some medicine alone. It must also cover the price tag on treating a complication which could arise while using an alternative drug. Example: Inside a one who insists on taking alcohol and yet has to be treated for depression is generally administered an SSRI drug because they drugs don’t potentiate the end results of alcohol, whereas another gang of anti-depressants (like tricyclics) may cause a fresh problem in such patients, which would require a various and expensive treatment. Therefore, it’s easier to prescribe the more expensive escitalopram as opposed to a cheaper tricyclic in such patients.
Simple treatment: The best mode of administration is preferred. If you have an alternative between an injection and oral administration, the second is preferred in the event the efficacy of the modes is comparable. Or, local application is preferred to the oral route where possible; e.g., antibiotic treating eye infections. Dosage and frequency of administration too are a key point to decide simple treatment.
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