The standards For Selecting Medication For A Patient

SINCE Wwii, medical science has progressed to a stage where competitive medications are available to treat precisely the same ailment in several people. This is not nearly brands (the trade issue) but generic drugs (the scientific issue). Within this report, we shall look at the various factors that decide your selection of a specific drug.

Safety: These sub-criteria have to be considered within the criterion of safety:

* Acute therapeutic index: In the event the patient’s condition is acute, how effective is really a particular drug even when it has certain side-effects so long as the acuteness in the condition is lowered? Example: narcotic pain-killers are amazing in healing pain but come with the possibility side-effect of addiction.

* Long-term safety: directory might be safe in short-term treatment, but wait, how safe it is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but could have undesirable effects in the event of prolonged use.

* Drug-drug interaction risk: Medicine is chemicals, and several chemicals answer make a different chemical, which has an effect that will harm the patient or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to generate a new condition that warrants separate treatment.

Drug-drug interaction risk is of 2 types:

· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, outside of each other, have certain effects using one or even more body processes (e.g., metabolism) that affects the performance in the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) depends upon for the metabolism. This leads to a boost in the side-effects of Lexapro.

· Pharmacodynamic: Here, two or more drugs actually generate the same effect on precisely the same organ, thus helping the total, added effect. Example: Lexapro has certain side-effects like drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of the two medicine is more intense.

Tolerability: A medicine might be effective and not tolerable by all patients. Example: Allergies to particular drugs in some people. Short-term and long-term tolerability should be considered. Efficacy: A medicine is not equally effective in all patients. As an example, some patients with depression or anxiety disorders experience reduced escitalopram, but there are numerous that do not, who therefore should be prescribed an alternative anti-depressant. The speed of oncoming of therapeutic action is an important key to be regarded as too.

Cost: Cost does not mean the price tag on buying a specific medicine alone. It will also cover the price tag on treating a complication that will arise from using an alternative drug. Example: In the individual who insists on taking alcohol nevertheless needs to be treated for depression is generally administered an SSRI drug since these drugs don’t potentiate the consequences of alcohol, whereas another gang of anti-depressants (like tricyclics) could cause a whole new problem in such patients, which could need a different and expensive treatment. Therefore, it’s easier to prescribe the more expensive escitalopram as opposed to a cheaper tricyclic such patients.

Simplicity of treatment: The simplest mode of administration is preferred. If you find a choice between a shot and oral administration, the latter is preferred if your efficacy of the two modes is analogous. Or, local application is preferred to the oral route where possible; e.g., antibiotic treating eye infections. Dosage and frequency of administration too are a key point to decide simplicity of treatment.
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